ISLAMABAD(National Times)- The Pakistan Ministry of Foreign Affairs has issued an emergency travel advisory, strongly urging its citizens to avoid all non-mandatory travel to the Islamic Republic of Iran. The move comes as the Middle East is plunged into a renewed and volatile military confrontation following a massive joint military operation by Israel and the United States against Iranian targets on Saturday. The Foreign Office has instructed Pakistani nationals currently residing in Iran to exercise extreme caution, remain vigilant, and minimize non-essential movement. Citizens have been directed to stay in constant communication with Pakistani diplomatic missions as the security situation remains fluid. The joint US-Israeli strikes represent a significant escalation after a twelve-day air war between Israel and Iran this past June. The attacks targeted several major Iranian cities, including the capital Tehran, Isfahan, Qom, Karaj, and Kermanshah. “The State of Israel launched a pre-emptive attack against Iran to remove threats to the State of Israel,” stated Defense Minister Israel Katz, confirming the commencement of the operation. While explosions rocked the capital, Iranian state media reported that the office of Supreme Leader Ayatollah Ali Khamenei was among the sites targeted. Reports suggest the Supreme Leader was not in Tehran at the time of the strike and has been relocated to a secure, undisclosed location.